Professor Avishai Wool presents a system that protects GNU/Linux machines from intrusion and malicious program code by using statistical analysis and policy files defining a programs normal behavior, and if that program deviates from said behavior the system stops it.
Since the analysis is hooked into standard GNU/Linux build tools and uses the source code to derive the policy the system is said to guarantee zero false positives. A system of this type is cited to be able to perform protection from threats long before traditional anti virus solutions has categorized them, and with far less penalty to system performance.
Here’s a list of links for further reading: